Defects Can Increase the Melting Temperature of DNA−Nanoparticle Assemblies
نویسندگان
چکیده
منابع مشابه
Defects can increase the melting temperature of DNA-nanoparticle assemblies.
DNA-gold nanoparticle assemblies have shown promise as an alternative technology to DNA microarrays for DNA detection and RNA profiling. Understanding the effect of DNA sequences on the melting temperature of the system is central to developing reliable detection technology. We studied the effects of DNA base-pairing defects, such as mismatches and deletions, on the melting temperature of DNA-n...
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In This paper, the effect of size on melting temperature of metallic nanoparticles (Au, Pb and Bi) is theoretically simulated and explained. In this regard, the cause of difference in various experimental data is introduced, which is the difference between nanoparticles’ grain Gaussian distribution. This volume-depended model with the help of the Gaussian distribution can descri...
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UNLABELLED MELTING computes the enthalpy and entropy of an oligonucleotide duplex helix-coil transition, and then its melting temperature. The program uses the method of nearest-neighbours. The set of thermodynamic parameters can be easily customized. The program provides several correction methods for the concentration of salt. MELTING is a free program, available at no cost and open-source. P...
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Many factors that change the temperature position and interval of the DNA helix-coil transition often also alter the shape of multi-peak differential melting curves (DMCs). For DNAs with a multi-peak DMC, there is no agreement on the most useful definition for the melting temperature, Tm, and temperature melting width, ΔT, of the entire DNA transition. Changes in Tm and ΔT can reflect unstable ...
متن کاملinfluence of size on the melting temperature of metallic nanoparticle
in this paper, the effect of size on melting temperature of metallic nanoparticles (au, pb and bi) is theoretically simulated and explained. in this regard, the cause of difference in various experimental data is introduced, which is the difference between nanoparticles’ grain gaussian distribution. this volume-depended model with the help of the gaussian distribution can describe the relation ...
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ژورنال
عنوان ژورنال: The Journal of Physical Chemistry B
سال: 2006
ISSN: 1520-6106,1520-5207
DOI: 10.1021/jp062287d